Effect of pumpkin enriched with calcium lactate on iron status in an animal model of postmenopausal osteoporosis

Abstract The homeostasis of calcium (Ca) and iron (Fe) is disturbed during menopause. present study aimed to determine the effects Ca-enriched pumpkin on Fe status in ovariectomized rats. A total 48 female Wistar rats were divided into six groups. One group was fed a standard diet (C), while other five groups (OVX), lactate (CaL_OVX), lactate-enriched (PCaL_OVX), alendronate (CaL_OVX_B), (PCaL_OVX_B), respectively. nutritional intervention lasted 12 weeks euthanized. Tissue samples collected, content assessed. comparison all showed reduction concentrations femurs, liver, hair, spleen, kidneys than control group. PCaL_OVX_B had significantly higher blood hemoglobin concentration Moreover, spleen liver highest PCaL_OVX among treated comparable with These results indicate that ovariectomy decreases Calcium without can increase